PALMOILMAGAZINE, BANDUNG – Asep Bayu, a researcher at the Expert Staff of the Vaccine and Drug Research Center under the National Research and Innovation Agency (BRIN), has successfully pioneered the development of an E super vitamin rich in tocotrienol. This breakthrough holds immense potential for cancer immunotherapy, offering both economic and biological advantages.
Utilizing palm oil, a key commodity in Indonesia, Asep Bayu leverages palm fatty acid distillate (PFAD), a byproduct of palm oil fatty acid, known for its exceptionally high tocotrienol content compared to other vegetable oils. Tocotrienol, with twice the biological activity of tocopherol, holds significant economic value.
In the research, as discussed in the Monitoring and Evaluation of Palm Oil Research Grant from the Palm Oil Plantation Fund Management Agency, the initial phase focused on tocotrienol extraction from PFAD. This process incorporated deep eutectic solvents (DES) and methanol to enhance the mass of vitamin components during extraction.
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“The first year – research showed that PFAD has antioxidant activity 2,5 higher than free tocotrienol. Nano emulsion of tocotrienol showed cytotoxic was against breast and lungs cancers within concentration 50 – 200 ppm,” Asep Bayu said, as in the official statement to Palmoilmagazine.com from the Public Relation of BRIN.
In the next years, Asep and his team planned to continue the research to get optimal condition in tocotrienol extraction by using the DES ChCl solvent in phenolic or betaine monohydrate group. Besides, they would focus on making NANOVITE formula to maximize E super vitamin potential as immune therapy.
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Indonesia, as the number one palm oil producer in the world saw the innovation as te positive one to get advantage on natural resource sustainably. In Covid-19 crude palm oil (CPO) exports escalated from Indonesia, it plays strategic roles of palm oil to the economy nationally.
The innovation is hoped to not escalate palm oil industrial values, but also open the new potential of health technology and be more effective to get cancer therapy. (T2)
